NON-SMALL CELL LUNG CANCER (NSCLC)
Lung cancer is the leading cause of cancer related deaths in the United States with 160,000 deaths annually being more than colon, breast & prostate cancer combined. 85% of lung cancer patients are diagnosed with non-small cell lung cancer (NSCLC) and roughly 75,000 people are newly diagnosed with stage 4 every year. Approximately only 50% of patients diagnosed with advanced, non-squamous NSCLC are candidates for targeted chemotherapy drugs or immunotherapy (circa 45,000 patients annually in the US). Hence, we see the significant unmet need for patients with late-stage disease requiring chemotherapy.
NSCLC may be broken down into three main subtypes: adenocarcinoma, squamous cell carcinoma and large cell carcinoma.